Dr. Eddie Myers

Education
Oct 2002–Oct 2002
Ph.D University of Bristol (2006) Prof. Varinder K. Aggarwal
Thesis Development of a Morita–Baylis–Hillman-type Reaction:Iminium Ions as Terminal Electrophiles
Sept 2000–Sept 2000
M.Sc. McGill University (2003) Advisor: Prof. Youla S. Tsantrizos
Thesis Synthesis of Heterocyclic Aromatic Peptide Nucleic Acids
Sept 1996–Sept 1996
B.A. Natural Science Trinity College Dublin (2000) 1st Class/Gold Medal Advisor: Prof. Youla S. Tsantrizos
Thesis Synthetic efforts towards an Actinomycin–Peptide Nucleic Acid (PNA) conjugate
Career / Research
Sept 2017–Present
Lecturer in Organic Chemistry School of Chemistry, NUI Galway
Sept 2014–Aug 2017
Research Officer Aggarwal Laboratory, University of Bristol
Sept 2012–Sept 2014
Associate Editor Chemistry—A European Journal, Wiley-VCH, Germany
Feb 2012–Sept 2012
Assistant Editor Angewandte Chemie, Wiley-VCH, Germany
Dec 2009–Dec 2011
LMU Research Fellow Ludwig Maximilian Universität, Munich, Germany, Laboratory of Prof. Dirk Trauner Department of Chemistry
Oct 2006–Nov 2009
Postdoctoral Associate University of Wisconsin–Madison, Madison WI, USA, Laboratory of Prof. Ronald T. Raines, Department of Biochemistry
Awards
  • LMU Research Fellowship (2009–2011)
  • Alexander von Humboldt Fellowship (2009, declined in favor of LMU Fellowship)
  • Dean’s Honor List, McGill University (2003)
  • T. Sterry Hunt Award for Excellence in Teaching, McGill University (2002 and 2001)
  • Alexander McFee Fellowship, McGill University (2001–2002)
  • Gold Medal, Trinity College (2000)
  • John Winthorp Hackett Moderatorship Prize (2000)
  • Cocker Prize and Medal, Trinity College (2000)
  • Graduate Award, Institute of Chemistry of Ireland (2000)
  • Dr. George A. Lonergan Prize, Trinity College (1999)
  • Elected Scholar of Trinity College (1998)
  • D.C. Pepper Prize in Chemistry, Trinity College (1998)
  • Henley Memorial Prize, Trinity College (1997)
  • Eli Lilly Chemistry Prize, Trinity College (1997)
Recent External Presentations
RSC South West Organic Division Meeting – University of Bath, UK – Feb 1 2017
Manuscripts/Publications/Patents
  1. Synthesis of Novel Analogs of Aromatic Peptide Nucleic Acids (APNAs) with Modified Conformational and Electrostatic Properties
    L. D. Fader, E. L. Myers, Y. S. Tsantrizos
    Tetrahedron, 2004, 60, 2235–2246.

  2. BF3 OEt2 and TMSOTf: A Synergistic Combination of Lewis Acids
    E. L. Myers, C. P. Butts, V. K. Aggarwal
    Chem. Commun, 2006, 4434–4436.

  3. Reactions of Iminium Ions with Michael Acceptors through a Morita–Baylis–Hillman-type reaction: Enantiocontrol and Applications in Synthesis
    E. L. Myers, J. G. de Vries, V. K. Aggarwal
    Angew. Chem. Int. Ed., 2007, 1893–1896.

  4. A New Manifold for the Morita Reaction: Diene Synthesis from Simple Aldehydes and Acrylates/ Acrylonitrile Mediated by Phosphines
    A. Palmelund, E. L. Myers, L. R. Tai, S. Tisserand, C. P. Butts, V. K. Aggarwal
    Chem. Commun., 2007, 4128-4130.

  5. Chalcogenides as Organocatalysts
    E. M. McGarrigle, E. L. Myers, O. Illa, M. A. Shaw, S. L. Riches, V. K. Aggarwal
    Chem. Rev., 2007, 107, 5841-5883.

  6. A Phosphine Mediated Conversion of Azides to Diazo Compounds
    E. L. Myers, R. T. Raines
    Angew. Chem. Int. Ed., 2009, 48, 2359-2363.

  7. Preparation of Diazo and Diazonium Compounds
    E. L. Myers, R. T. Raines
    US Patent 20130203974 A1,

  8. Selected Diastereoselective Reactions: Electrocyclizations
    E. L. Myers, D. Trauner
    Comprehensive Chirality (Eds.: E. M. Carreira, H. Yamamoto, J. Mulzer), Vol. 2, Elsevier, Amsterdam, Oxford, Waltham, pp. 563-562.

  9. Total Synthesis of the Proposed Structure of Trichodermatide A
    E. L. Myers, E. Herrero-Gómez I. Albrecht, J. Lachs, P. Mayer, M. Hanni, C. Ochsenfeld, D. Trauner
    J. Org. Chem., 2014, 79, 9812-9817.

  10. Synthesis of 3-Aryl-1-aminopropane Derivatives: Lithiation-Borylation-Ring-Opening of Azetidinium Ions
    G. Casoni, E. L. Myers, V. K. Aggarwal
    Synthesis, 2016, 48, 3241-3253.

  11. Enantiospecific Alkynylation of Alkylboronic Esters
    Y. Wang, A. Noble, E. L. Myers, V. K. Aggarwal
    Angew. Chem. Int. Ed., 2016, 55, 4270-4274.

  12. Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation– borylation conditions
    D. J. Blair, S. Zhong, M. J. Hesse, N. Zabaleta, E. L. Myers, V. K. Aggarwal
    Chem. Commun, 2016, 52, 5289-5292.

  13. Regio- and Stereoselective Homologation of 1,2-Bis(Boronic Esters): Stereocontrolled Synthesis of 1,3-Diols and Sch 725674
    A. Fawcett, D. Nitsch, M. Ali, J. Bateman, E. L. Myers, V. K. Aggarwal
    Angew. Chem. Int. Ed., 2016, 55, 4270-4274.

  14. Stereodivergent Olefination of Enantioenriched Boronic Esters
    R. Armstrong, C. García-Ruiz, E. L. Myers, V. K. Aggarwal
    Angew. Chem. Int. Ed., 2017, 56, 804-808.

  15. Iterative Assembly-line Synthesis of Polypropionates with Full Stereocontrol
    T. Bootwicha, J. M. Feilner, E. L. Myers, Varinder K. Aggarwal
    Nature Chem., 2017, 9, 896-902.

  16. Selective Uni- and Bidirectional Homologation of Diborylmethane
    D. J. Blair, D. Tanini, J. M. Bateman, H. K. Scott, E. L. Myers, Varinder K. Aggarwal
    Chem. Sci., 2017, 8, 2898-2903.

  17. Asymmetric Synthesis of Secondary and Tertiary Boronic Esters
    B. S. L. Collins, C. M. Wilson, E. L. Myers, V. K. Aggarwal
    Angew. Chem. Int. Ed., 2017, 56, 11700-11733.

  18. Photoinduced Decarboxylative Borylation of Carboxylic Acids
    A. Fawcett, J. Pradeilles, Y. Wang, T. Mutsuga, E. L. Myers, V. K. Aggarwal
    Science, 2017, 357, 283-286.

  19. Synergy of synthesis, computation and NMR reveals correct baulamycin structures
    J. Wu, P. Lorenzo, S. Zhong, M. Ali, C. P. Butts, E. L. Myers, V. K. Aggarwal
    Nature, 2017, 547, 436-440.

  20. Enantiospecific Synthesis of ortho-Substituted Benzylic Boronic Esters by a 1,2-Metalate Rearrangement/1,3-Borotropic Shift Sequence
    S. Aichhorn, R. Bigler, E. L. Myers, V. K. Aggarwal
    J. Am. Chem. Soc., 2017, 139, 9519-9522.

  21. Enantioselective Rhodium(III)-Catalyzed Markovnikov Hydroboration of Unactivated Terminal Alkenes
    J. R. Smith, B. S. L. Collins, M. J. Hesse, M. A. Graham, E. L. Myers, V. K. Aggarwal
    J. Am. Chem. Soc., 2017, 139, 9148-9151.

  22. α-Sulfinyl Benzoates as Precursors to Li and Mg Carbenoids for the Stereoselective Iterative Homologation of Boronic Esters
    G. Casoni, M. Kucukdisli, J. M. Fordham, M. Burns, E. L. Myers, V. K. Aggarwal
    J. Am. Chem. Soc., 2017, 139, 11877-11866.